A deficiency of folic acid can lead to a type of anemia called,
Pernicious Anemia. This anemia is characterized by having red blood
cells that are impaired in their abilities to carry oxygen, which
leads to a slow and chronic deprivation of oxygen to all of the
cells of your body.
Signs of Pernicious Anemia are fatigue, gastrointestinal
disorders(particularly diarhhea), and partial loss of coordination
in the fingers, feet and limbs. There may be a loss of appetite,
and the skin can have a pale or flushed look about it. In severe
cases of anemia this can lead to eventual death.
Other symptoms of a folic acid deficiency include:
mouth sores, metabolic changes, and increased chance of birth defects
and problems with the mucosa membranes.
It is also possible to develop Pernicious Anemia
if you have a deficiency of the vitamins, B12 and B7. In fact folic
acid is so effective at treating anemia that if you take too much
of it, it can mask the anemia caused by a deficiency of one of these
other two vitamins. This can lead to severe damage as folic acid
is not a replacement for these other two vitamins and is not treating
the deficiency, simply the symptom of deficiency in the case of
vitamins, B12 and B7. The dangers of masking these two vitamin deficiency
are that the other symptoms will continue. Vitamin B12 deficiency
can lead to fatigue and depression. Its also been linked to Alzheimer's
and other forms of dementia and Vitamin B7. deficiency can lead
to depression, brittle nails and skin disorders and muscle cramps.
Due to this danger of masking other vitamin deficiencies
there has been an upper limit intake (UL) set for folic acid. This
limit is one thousand mcg. daily of folic acid. A normal adult is
recommended to take four hundred mcg. daily and a woman who could
become pregnent, is pregnent or is lactating should take between
six hundred and eight hundred mcg. daily of folic acid.
Because folic acid is effective at treating anemia
it is sometimes prescribed by doctors to treat anemia symptoms caused
by other conditions. Interestingly folic acid was first discovered
because a Dr. Lucy Wills noted that a substance in Brewer's Yeast
appeared to correct the condition of anemia in pregnant women. This
substance was folic acid.
The primary cause of a folic acid deficiency is
poor diet, but currently governments in the U.S., Britain and other
countries are requiring that foods be fortiefied with folic acid
or folate as it is sometimes called. This fortification greatly
reduces the chances that someone in these countries will delevop
a folic acid deficiency and the ensuing anemia. Foods that are fortified
with folic acid are, breakfast cereals, some grain products and
wheat flour.
Of course it is possible to get your RDA of folic
acid from the foods that you eat. Such foods high in folic acid
are green leafy veggies, wheat germ, peas and other legumes, and
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